After entering into the 6th year of the pandemic, the virus is evolving. The fatalities reported daily in the United States alone have increased from the staggering 5000+ reported each day in the year 2021 to 280 of the reported mortalities each and every day towards the end of February month this year. Still, the pandemic is having a profound impact on reshaping the societal dynamics.

The lives of millions of individuals have changed due to the loss of their loved ones, which caused several illnesses, economic burdens & detrimental impacts on mental health. The challenge that lies ahead of humanity is due to the capability of the Coronavirus to evolve, posing a constant threat. It will be more challenging for old age people, individuals having medical commodities, and the ones whose immunity has already been compromised, so everyone will be at risk of coming into the grip of this virus, with the potential of mortality.

IVERMECTIN ACTING AN ORAL ANTIVIRALS IN MANAGING COVID-19 SYMPTOMS & PREVENTING HOSPITALIZATION

• The challenge that lies ahead of humanity is due to the capability of the Coronavirus to evolve, posing a constant threat.
• It will be more challenging for old age people, individuals having medical commodities, and those whose immunity has already been compromised, so everyone will be at risk of coming into the grip of this virus, with the potential of mortality.
• As per the epidemiological reporting from World Health Organization, WHO, the globalized cases of the pandemic has witnessed the slight up stick since April. This has led to a 10% enhancement in the cases every week in comparison to the previous month March 2025.

TREATMENT OPTIONS FOR COVID-19: Can Ivermectin be a choice?

• Today there are many treatment provisions available for COVID-19 for preventing hospitalization as well as serious complications.
• The first line of treatment is the administration of oral antivirals for the management of the symptoms, and arresting the virus from spreading to the different parts of the body through the management of the immuno-responsiveness of the body.
• Ivermectin (Covimectin), FDA approved, wide-spectrum antiparasitic drug over the years has demonstrated antiviral activity.
• With applicability as a therapeutic measure for different parasitic infections like onchocerciasis, strongyloidiasis as well as other kinds of disorders taking place due to the soil-transmitted helminthiasis, scabies, etc. there is an exploration of the in vitro antiviral action of ivermectin against the spectrum of disorders. This includes the severe acute respiratory syndrome due to COVID. In consideration of the ongoing, increasing cases of new mutant strains of novel coronavirus, repurposed drug, Ivermectin is definitely be worth getting attention.

 In this blog post of today, let’s find out what ivermectin is, why it has been repurposed for the elimination of the coronavirus, what its benefits are & what role it is playing against SARS COVID-2 virus.

WHAT IS IVERMECTIN?

• Ivermectin, an anti-parasitic drug falling in the group of avermectins, is indicated for curing intestinal helminths as well as infections due to filarial worms in animals and human beings.
• It was successful in treating patients including the incidences of parasitic infections in low-income countries and also falls into the model list of the essential medications of WHO.

USES OF IVERMECTIN FOR SARS-COV-2

A review conducted by the Frontline Critical Care Alliance of COVID-19 concluded that ivermectin is demonstrating a strong signaling efficacy against viral infections due to COVID-19. And was able to reduce the mortality to the extent of 75%.

ACTION MECHANISM OF IVERMECTIN AGAINST SARS- COV-2

• The antiparasitic, human, and animal care drug is exhibiting antiviral activity against the assortment of the genetic material of several viruses.
• The host direct mechanism of ivermectin is suggested that is leading to the blockage of the nuclear Import of the genetic material of the virus, leading to the suppression of the immune responsiveness.

IVERMECTIN DOSAGE FORMS

• Ivermectin 3 mg
• Ivecop 12mg (Ivermectin)
• Ivermectin 24mg (Covilife)
• Ivermectin 6 mg
• Ivermectin 12 mg
• Iverheal
• Covimectin 12 mg
• Iversun 12 mg

EFFECTIVENESS OF IVERMECTIN IN COMBATING SARS- COV-2 & ASSOCIATED RISKS

• There are around 100 studies that have been conducted using ivermectin and has demonstrated a success rate of more than 80% within prophylaxis as well as 62% during the early course of the therapeutic procedure. In fact, Ivermectin has already been approved for the early treatment procedure for the covid-19 pandemic in as many as 28 countries.
• There are many of clinical trials and ongoing researchers going on in the assessment of this medicine for treating COVID-19.
• Many of Countries of South America, Southeast Asia, European Nations, and recently Slovakia have already implemented the guidelines for using Covimectin for treating Covid-19.
• Since it is not a newly developed, experimental medication with an already established safety profile, it can be quite an equitable, widely acceptable, and feasible intervention for SARS-CoV-2 at a global level.
• And thus it is important for Healthcare professionals globally to consider the utilization of this WHO essential listed medicine, utilized for many different indications already.

CONCLUSION

• Developing the new COVID medications can take several years and therefore the emphasis is on repurposing the existing drugs for the treatment.
• Ivermectin, owing to its highly established safety profile, with many years of usage plays a critical role in the suppression and treatment of the patient having SARS-CoV-2 pandemic.

At the same time, Ivermectin with commercial availability and cost effectiveness plays an important role in treating patients in settings having the limited resources.

Frequently Asked Questions (FAQs) on effectiveness of Ivermectin for SARS-COV-2

• Can ivermectin help in the management of post-COVID-19 symptoms?

There have been reports suggesting that through the escalation of the Ivermectin dosage, 0.2 mg per Kg & 0.4 mg/Kg for the symptoms ranging from mild to moderate, in 87% of the patients there was resolution of the symptoms after the consumption of the two dosages of the antiparasitic drug.

• What are possible side effects of ivermectin?

Some of the side effects of covimectin include:

• Itchiness in skin
• Feeling of giddiness
• Sensation of vomiting
• Difficulty while passing stool
• Low energetic level
• Alteration in the rhythmic rate of the heart

• Can ivermectin result in clotting of blood?

The Ivermectin drug has a minimal level of impact on the coagulation of the blood. In fact, this human and animal care product has an interfering impact on the coagulation process. This is more common in people who are malnourished, where there is a deficiency of Vitamin K preceding the treatment procedure.