Today, many people are looking forward to alternative therapies for cancer treatment. The ivermectin and Fenbendazole, primitive antiparasitic drugs, have been repurposed due to their promising potential in the therapeutic effect of cancer.

Promising Potential of Ivermectin & Fenbendazole for Cancer Cure

  • In the year 2015, the researchers won the Nobel Prize for the discovery of this novel antiparasitic therapy, ivermectin. The ivermectin and Fenbendazole are found to demonstrate broad activity against many different categories of parasitic worms infecting animals like dogs, cats, horses, livestock & farm animals.
  • The 2 de wormers have got FDA approval for use in veterinary and human medicine for controlling parasitic infections.

 In this blog post of today, let’s find out the history of these versatile drugs, their use for animals, mode of action on different parasitic nematodes, dosages, side effects, and much more!

Keep reading the blog post to get more useful & practical information:

What are ivermectin & fenbendazole?

  • Both ivermectin & fenbendazole are two of the most common as well as preventive antiparasitic formulations to be used in animals and also human beings. In fact, it is rendered to the dogs as a part of the worm infection preventive plan.
  • The 2 dewormers show effectiveness against many different kinds of worms infecting animals, for example, intestinal parasites, ticks, mites, heartworm, micro-filarial infections, nematodes, arthropods, Protozoa, and others.

Uses of ivermectin in treating parasitic infections in animals

Ivermectin is effective against worm infections taking place due to nematodes, mites, and lice infection due to arthropods and others.

Uses of Fenbendazole for curing parasitic infections treatment in animals

  • Fenbendazole has its application for both large as well as small-sized animals.
  • For example, in dogs, it is beneficial for treating infections of roundworms, tapeworms, for instance, taenia species, hookworms, and other challenging with worms to treat.
  • In case the pet is having chronic diarrhea, and the cause is worm infection, then this antiparasitic drug is administered for several days within a row.

Use of ivermectin & Fenbendazole for cancer cure

  • Ivermectin is found to effectively target tumor cells, and dosages which is not harmful to humans & animals. So, it can be safely administered in combination with the conventional therapies.
  • The Fenbendazole is serving as a moderate stabilizing component, while possessing the anti-tumor impact.
  • The de-wormer leads to the eruption of the tumor cell through the modulation of multiple of cellular pathways.

Mechanism of action of Ivermectin for worm infection treatment in animals

  • The ivermectin for animal cure is acting through the binding of the glutamate-gated gated channels of chloride within worms.
  • This actually causes the targeting of the external parasites, for example, ticks, mites, and also internal worms within pets and livestock.

Mechanism of action of Fenbendazole for killing parasites in animals

  • The Fenbendazole is demonstrating action through the disruption of the synthesis of the microtubule within the parasitic cells invading animals.
  • This leads to the inhibition of the metabolic processes as well as reproduction in parasites, eventually leading to their death.

Route of administration of ivermectin & Fenbendazole to animals

    How to give ivermectin dewormer to animals- veterinary advice

    • Ivermectin could be administered in the form of oral tablets or liquid suspensions.
    • Also, the route of Administration can be ointments or pour-on solutions

    What is the best way to administer Fenbendazole to dogs, cats, horses, cattle, livestock & other big animals?

    This dewormer could be administered in the form of oral granules, suspensions, injectable forms, or tablets, which can be rendered by mixing with food/ water

    Ivermectin protocol for parasitic cleanse

    Strongyloidiasis   0.2 mg/ Kg for administration of single dose
    Onchocerciasis           0.5 mg/Kg for administration of single dosage
    scabies0.2 mg/Kg in the tablet formula for two doses every 15 days
    Rosacea inflammatory lesions   1% cream applicable on daily on

    Ivermectin dosage and Protocol for cancer

    • ovarian cancer-12 mg IVM for 2 months
    • Cancer of the Brain -1-2 mg/kg/day Breast Cancer-2 mg/kg/day Cancer of Spine- 0.5 mg/kg/day Cancer of the Prostate- Ivermectin 4.5 mg daily for two months Lung Cancer – Ivermectin 12 mg daily for three months Liver and colon cancer-Ivermectin 24 mg twice daily Cancer of the cervical region – IVM 12 mg daily for two weeks
    • Fenbendazole Dosage & Protocol for treatment for cancer It is necessary to take a 222 mg/day fenbendazole pill every day after consuming a fatty meal. The Fenbendazole Protocol to Prevent Recurrence of Cancer 222 mg Fenbendazole capsules are given once daily for three days during a week following the consumption of a fatty diet. It is discovered that the single dosage of 222 mg per day is well tolerated. The daily dosage of fenbendazole can be raised to 444 mg.

    Safety & side effects of ivermectin and Fenbendazole in animals

    Both antiparasitic formulations commonly utilized for animal treatment are generally considered safe when administered under the supervision of a veterinary doctor. There can be minimal or no side effects, for example:

    • Dizziness
    • Nausea
    • Loss of appetite
    • Allergic reactivity
    • Increase the sensitivity of a few dog breeds to hereditary mutation

    Concerns and precautions while administering ivermectin and Fenbendazole to pets

    • The treatment protocol of both ivermectin & Fenbendazole for animal use should be decided by a veterinary doctor. Ideally, treatment for deworming animals is considered for 3-5 days for eradicating most of the parasites.
    • There might be a requirement for the second course, on the basis of the animal’s responsiveness & type of the condition to be treated.
    • It is advisable to render ivermectin/Fenbendazole dosage and protocol with food to facilitate the best possible absorption by the animal body.
    • You can source Ivermectin & Fenbendazole from Safe Generic Life Pharmacy.

    Frequently Asked Questions- (FAQs)

    Can I administer Fenbendazole to a dog of any breed?

    In the majority of cases, Fenbendazole is safe and well-tolerated by all breeds of dogs. This includes pregnant pets as well as puppies.

    In case of ivermectin, caution with some herding breeds is needed, as it can cause adverse reactions. Talk to the veterinary doctor before starting deworming treatment for your pet.

    How does one administer ivermectin to dogs?

    Ivermectin and Fenbendazole are both given orally as tablets, liquids, or injections.